Health Insights · Dermatology

Perioral dermatitis: a rash around the mouth

Perioral dermatitis is a rash of small red bumps and scaling around the mouth, nose or eyes, typically sparing a narrow border right at the lip edge. It is frequently mistaken for acne or eczema and treated with steroid cream — which settles it briefly and then makes it considerably worse.

Seek assessment rather than self-treating if there is

  • involvement around the eyes with redness or discomfort of the eye itself
  • weeping, crusting or spreading redness, suggesting infection
  • a rash with fever or feeling unwell
  • blistering, or painful clustered vesicles
  • no improvement after eight weeks of appropriate treatment

Around the eyes this is called periocular dermatitis and needs the same approach. Clustered blisters may be a herpes infection, which requires antiviral treatment rather than anything used for dermatitis.

The steroid trap

Topical steroids are the commonest cause. They suppress the rash within days, so it looks like the right treatment — then the rash returns worse when they are stopped or the strength wears off, prompting more steroid. The cycle can run for years. Inhaled steroids for asthma and steroid nasal sprays can do the same thing if they deposit around the mouth or nose, which is a connection almost nobody makes. The treatment is stopping the steroid, and being prepared for what happens next.

Recognising it

  • clusters of small red bumps and pustules with fine scaling
  • around the mouth, nostrils, chin, sometimes the eyelids
  • a clear rim of normal skin immediately next to the lip border — the most characteristic sign
  • burning or stinging rather than itching
  • no blackheads, which distinguishes it from acne
  • commonest in women aged 20 to 45, and in children using steroid creams

Zero therapy

The first step is to stop everything on the face except water. That means no steroid creams, no heavy moisturisers, no foundation or tinted products, no cleansers, no fluoride toothpaste against the skin, no exfoliants and no active ingredients.

Expect it to flare before it improves

When the steroid stops, the rash rebounds — often dramatically, within days, and worse than before. This is expected, it is the condition unmasking, and it is not a reason to restart the cream. It settles over two to six weeks. Knowing this in advance is the difference between people getting through it and abandoning treatment. Where the rebound is severe, the steroid can be tapered rather than stopped abruptly, or an oral antibiotic started at the same time to cover it.

Treatment

  • Topical treatment — metronidazole, azelaic acid or ivermectin, for mild cases, over six to twelve weeks.
  • Oral antibiotics — a tetracycline at anti-inflammatory dose for six to twelve weeks for moderate or severe cases, or where the rebound is likely to be difficult. Not used in children under 12 or in pregnancy, where alternatives exist.
  • Bland emollient only if the skin feels tight, and mineral sunscreen if needed.
  • Improvement usually begins at three to four weeks and continues for months.
  • Recurrence is common if steroids are used on the face again — which is worth remembering when any clinician offers one.

Afterwards

  • Reintroduce products one at a time, weeks apart, and keep the routine simple.
  • Avoid heavy occlusive creams and thick foundations on the affected area.
  • If you use a steroid inhaler, rinse your mouth and wash your face afterwards.
  • Tell any clinician treating your face that you have had perioral dermatitis.

Why come to us. This is a condition where the wrong treatment is the cause, and the right treatment feels wrong for the first fortnight. Our dermatology team will confirm the diagnosis rather than treating it as acne or eczema, prescribe the topical and oral treatments that work, plan the steroid withdrawal so the rebound is manageable, and review you at the point it usually gets hardest. No referral needed, 7 days a week.

Private treatment for perioral dermatitis in London

Perioral dermatitis is a bumpy rash around the mouth that is often worsened by steroid creams and certain skincare, so the right approach matters. Our private dermatology clinic in London can diagnose it and guide treatment, and a private GP in East London can start care and advise on stopping aggravating products. Perioral dermatitis is assessed at our Whitechapel hospital in East London, close to Canary Wharf, Bethnal Green and the City.

Perioral dermatitis: treating a stubborn facial rash

What makes perioral dermatitis worse?

Steroid creams, heavy or occlusive skincare, and some toothpastes can worsen it; stopping these is part of treatment.

How is it treated?

Usually by stopping triggers and using a prescribed course of treatment; it can take several weeks to settle.

Is it the same as acne or eczema?

No — it can look similar but is treated differently, which is why an accurate diagnosis helps.

Do I need a referral?

No — you can book dermatology directly or start with a private GP.

Is there a private dermatologist near me for a facial rash?

Yes — our private dermatology clinic in London at Whitechapel, near Canary Wharf, can diagnose perioral dermatitis and prescribe the right treatment.

Why did my facial rash get worse with steroid cream?

Steroid creams often worsen perioral dermatitis; our dermatology team can guide you through stopping them safely and treating the rash.

Diagnosed correctly, and supported through the rebound

Dermatology without a referral, 7 days a week.

↓ Download the printable PDF leaflet
Medically reviewed by Dr Haydar Bolat · GMC 7138332Content last reviewed: August 2026 · Next review due: August 2027Written and reviewed in line with our editorial & content-review policy, using guidance from sources such as the NHS, NICE and the relevant royal colleges. This information is for general guidance and does not replace personal medical advice — please book a consultation to discuss your circumstances.

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Our Whitechapel clinic at 97–99 Whitechapel Road, E1 cares for patients from right across London and East London, the City and the Docklands — including Aldgate, Bethnal Green, Bow, Shoreditch, Canary Wharf, Stratford, Bermondsey and the surrounding areas. Appointments are available seven days a week, self-pay with no health insurance needed, and most services need no GP referral.

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Book an appointment or call 020 7916 0029. See our transparent fees. Open 7 days a week, 9am–7pm. Private clinic on Whitechapel Road, London E1 — serving Tower Hamlets, Hackney, Newham, Islington, the City of London and Southwark.

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