Patient information · Dermatology
Perioral dermatitis
the rash that steroid cream causes and appears to cure
Perioral dermatitis is a rash of small red bumps and scaling around the mouth, nose or eyes, typically sparing a narrow border right at the lip edge. It is frequently mistaken for acne or eczema and treated with steroid cream — which settles it briefly and then makes it considerably worse.
Seek assessment rather than self-treating if there is
- involvement around the eyes with redness or discomfort of the eye itself
- weeping, crusting or spreading redness, suggesting infection
- a rash with fever or feeling unwell
- blistering, or painful clustered vesicles
- no improvement after eight weeks of appropriate treatment
Around the eyes this is called periocular dermatitis and needs the same approach. Clustered blisters may be a herpes infection, which requires antiviral treatment rather than anything used for dermatitis.
The steroid trap
Topical steroids are the commonest cause. They suppress the rash within days, so it looks like the right treatment — then the rash returns worse when they are stopped or the strength wears off, prompting more steroid. The cycle can run for years. Inhaled steroids for asthma and steroid nasal sprays can do the same thing if they deposit around the mouth or nose, which is a connection almost nobody makes. The treatment is stopping the steroid, and being prepared for what happens next.
Recognising it
- clusters of small red bumps and pustules with fine scaling
- around the mouth, nostrils, chin, sometimes the eyelids
- a clear rim of normal skin immediately next to the lip border — the most characteristic sign
- burning or stinging rather than itching
- no blackheads, which distinguishes it from acne
- commonest in women aged 20 to 45, and in children using steroid creams
Zero therapy
The first step is to stop everything on the face except water. That means no steroid creams, no heavy moisturisers, no foundation or tinted products, no cleansers, no fluoride toothpaste against the skin, no exfoliants and no active ingredients.
Expect it to flare before it improves
When the steroid stops, the rash rebounds — often dramatically, within days, and worse than before. This is expected, it is the condition unmasking, and it is not a reason to restart the cream. It settles over two to six weeks. Knowing this in advance is the difference between people getting through it and abandoning treatment. Where the rebound is severe, the steroid can be tapered rather than stopped abruptly, or an oral antibiotic started at the same time to cover it.
Treatment
- Topical treatment — metronidazole, azelaic acid or ivermectin, for mild cases, over six to twelve weeks.
- Oral antibiotics — a tetracycline at anti-inflammatory dose for six to twelve weeks for moderate or severe cases, or where the rebound is likely to be difficult. Not used in children under 12 or in pregnancy, where alternatives exist.
- Bland emollient only if the skin feels tight, and mineral sunscreen if needed.
- Improvement usually begins at three to four weeks and continues for months.
- Recurrence is common if steroids are used on the face again — which is worth remembering when any clinician offers one.
Afterwards
- Reintroduce products one at a time, weeks apart, and keep the routine simple.
- Avoid heavy occlusive creams and thick foundations on the affected area.
- If you use a steroid inhaler, rinse your mouth and wash your face afterwards.
- Tell any clinician treating your face that you have had perioral dermatitis.
Why come to us. This is a condition where the wrong treatment is the cause, and the right treatment feels wrong for the first fortnight. Our dermatology team will confirm the diagnosis rather than treating it as acne or eczema, prescribe the topical and oral treatments that work, plan the steroid withdrawal so the rebound is manageable, and review you at the point it usually gets hardest. No referral needed, seven days a week.
Diagnosed correctly, and supported through the rebound
Dermatology without a referral, seven days a week.
Tower Bridge Hospital London
97–99 Whitechapel Road, London E1 1DT
WhatsApp 07903 284 189
info@mhwclinic.co.uk
Open Mon–Sat, 9am–7pm (closed Sundays until September)
In an emergency
Call 999, or go to the Royal London Hospital Emergency Department, Whitechapel Road, London E1 1FR.
When we are closed and it is not an emergency
Call NHS 111 or visit 111.nhs.uk.